I drink a casin shake every night for past 20 years Mercola also mentions in another video to avoid whey isolate saying that it doesn't get absorbed correctly and can cause damage from build up. I haven't found further information on that yet. This Fitness Food Helps Improve Your Post-Exercise Recovery By Dr. Mercola A recent study looked at the role of protein in modulating post-exercise overnight recovery. The researchers assessed the impact of protein ingestion immediately prior to sleep on digestion, absorption kinetics, and protein metabolism on 16 healthy young males. The participants were asked to perform resistance exercises at 8pm in the evening. At 9pm, all participants ate a recovery meal consisting of 20 grams of protein and 60 grams of carbs. Then, 30 minutes before they went to bed, half of them drank a high-protein beverage. According to the authorsi: "During sleep casein protein was effectively digested and absorbed resulting in a rapid rise in circulating amino acid levels which were sustained throughout the remainder of the night. protein ingestion prior to sleep increased whole-body protein synthesis rates and improved net protein balance... This is the first study to show that protein ingested immediately prior to sleep is effectively digested and absorbed, thereby stimulating muscle protein synthesis and improving whole-body proteinbalance during post-exercise, overnight recovery."