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Fat loss and AAS (Is there some real truth?)

Discussion in 'Anabolic Hormones' started by Vision, Jun 7, 2017.

  1. Vision

    Vision ★★P.S.L. Supervisor★★Vendor Rep

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    Over the years there's been a massive debates, and of lately there's been some discussions in many of the panels in regards to AAS and fat loss..Some in the gear world populace are advocating that there's "no such thing", or AAS don't burn fat..

    So, let's discuss this... (AAS only, no stims or bata's,or GH)

    Now, you're gonna hear mix reviews on this.. However, I have seen enough evidence that supports AAS having,creating a environment/platform for fat burning..DIET without a doubt is crucial, and the pivotal player..However, there is real science behind fat loss and AAS, but please don't put all your money on it solely as an effective combatant..But nonetheless AAS is effective!

    As many of us should know "nutrient partitioning" is one of many parts and mechanisms, its a cascade of events with nutrients being shuttled is a huge factor in which effects are taking place..

    But lets talk about what AAS can do, the possibilities, and the capabilities that are astonishing the medical research field and athletes worldwide..

    Truth is; Science knows more about the cosmos than they do with hormones, we're merely scratching the service and there's always newer data/clinical studies out-dating an others contradicting each other and so on, but its only getting better and more advanced with actually explanations if you dig deep enough and care to understand.. One Dr my cite this, as an other cites that, just know what how to decipher what you're hearing/reading and research your research.

    AAS that are seen/recognized on the high/or moderate androgenic scale will in fact promote/increase lypolysis..Thus andros have a higher binding affinity to AR's..

    FYI; Androgen receptors are found throughout cellular groups, as well as FAT and muscle cell/groups, now we know that they initiate a response on AR's in muscle cells to promote size/growth, at the same given time they will have a cascade of effects on other cells and AR's found therein fat cells inducing activity/burning..


    Higher/more potent the androgen binds to the androgen receptors, the greater the lipolytic response will be on adipose tissue (brown or white)...

    Now lets also take into great consideration AR upregulation with the presence of androgens, more AR sites throughout targeting tissue..,There's a vast amount of activity in which a complex interplay between activation and inactivation mechanisms and signaling between cell groups, what People need to remember that hormones are "chemical messengers" that rely messages to cells that display specific receptors for each hormone and respond to the signaling..Depending on the compounds and the individuals metabolization ratio the hormone can/may make changes directly to a cell, by changing the genes that are activated, or by making changes indirectly to a cell by stimulating other signaling pathways inside a specific cell group that is effected and effect other processes, thus this can "initiate" an intracellular cascade of events.. So, the notion that fat Loss is NOT presence, and to mitigate that AAS don't posses any fat loss properties is absurd...

    So, yes AAS may assist with fat loss, however don't expect miracles and it's advised to have a lower body fat% by diet to expect to see more fat loss effects, but its not crucial..Have your macro's dialed in with your AAS intake, cardio ,and anything is possible, we've seen amazing things happen in this lifestyle..Even a couch potato can see results (whether it's deserving or not is a completely different topic)

    There's an abundance of clinical research and peer-reviewed data that strongly supports testosterone (and other AAS) fat reducing actions and its preventative impact on adipocyte generation...As AAS (especially Testosterone) acts both in the breakdown of existing fat tissue and to hinder pre-adipocytes from maturing.

    This is where some AAS began you acquire there reputation, or spin a myth (winstrol) at promoting fat loss, and achieve lower body fat,cuts..With this said, there's some truth behind winstrol and cuts, but not directly!

    Share you thoughts and experience with this!

    __________________________________________________

    Below is some studies conducted in fat loss, one in particular stresses the relation with diet and TRT and others just on a placebo and diet...The outcome is astonishing!!

    Testosterone Treatment Combined With Diet Reduces Fat, Maintains Muscle

    April 5, 2016

    By Frances Morin

    BOSTON -- April 5, 2016 -- Obese men treated with testosterone in addition to a low-calorie diet show greater reduction in body fat and less loss of muscle mass than men on similar diets who did not receive testosterone, according to a study presented here at the 98th Annual Meeting of the Endocrine Society (ENDO).
    “In men successfully losing weight through diet, both lean and fat mass are lost,” said Mark Ng Tang Fui, MBBS, BMedSc, The University of Melbourne, Heidelberg, Australia, on April 3.
    “The addition of testosterone prevents the loss of lean mass and shifts weight loss to almost exclusive loss of fat,” he added.
    Obesity has been linked to lower testosterone levels, whereas weight loss resulting from calorie restriction is linked to increases in circulating testosterone, noted the researchers. At the same time, weight loss in middle-aged men typically depletes fat and muscle.
    Although testosterone treatment has been also shown to reduce fat mass, the effects of combining testosterone treatment with calorie restriction have not been demonstrated.
    For the study, the researchers enrolled 100 obese men (body mass index [BMI], >30 kg/m2), aged 18 to 75 years, with low to low-normal serum total testosterone levels (average of 2 consecutive morning fasting levels of <12 nmol/L [<346 ng/dL]).
    The men were all placed on a very-low-calorie diet (~600 kcal/day) for 10 weeks, followed by a maintenance period of 46 weeks. They were randomised 1:1 in a blinded fashion to receive intramuscular testosterone 1,000 mg or placebo injections at baseline, week 6, and every 6 weeks thereafter over the 56 weeks of the study.
    At the study’s end, weight loss in both groups was similar, ie, an average of 11 kg (24.2 lb; P < .05 vs baseline). However, patients in the testosterone group lost 3 kg (6.6 lb) more body fat than those in the placebo group (P = .05) and lost significantly less lean mass than those in the placebo group (P = .001).
    Patients in the testosterone group also lost significantly more visceral adipose tissue at week 56 (P < .05).
    “We found that testosterone treatment reduces fat mass in obese men with a low testosterone level, more than the effects of diet alone,” concluded Dr. Fui. “Testosterone treatment also reduces visceral fat, more than the effects of diet alone, and prevents diet-associated loss of lean mass and muscle function.”
    “Although these changes are expected to be metabolically favourable, further trials in this population need to determine cardiometabolic and other benefits weighed against potential adverse effects,” Dr. Fui added.
    [Presentation title: Effect of Testosterone Therapy Combined With a Very Low Caloric Diet on Fat Mass in Obese Men With a Low to Low-Normal Testosterone Level: A Randomized Controlled Trial. Abstract LB-OR02-1]

    ____________________________________________


    Testosterone therapy in hypogonadal men results in sustained and clinically meaningful weight loss

    Abstract

    WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT:

    Hypogonadism is associated with increased fat mass and reduced muscle mass, which contributes to obesity and health risks, such as cardiovascular disease.Testosterone treatment of hypogonadal men improves muscle mass and reduces fat mass; however, many of these studies are of short duration.Thus, the long-term effects of testosterone on body anthropometry are not known.

    WHAT THIS STUDY ADDS:


    Long-term testosterone treatment of hypogonadal men, up to 5 years duration, produced marked and significant decrease in body weight, waist circumference and body mass index. Hypogonadism contributes to reduced muscle mass and increased adiposity.Testosterone treatment ameliorates loss of muscle mass and reduces fat accumulation associated with hypogonadism. In this study, we evaluated the long-term effects of normalizing testosterone (T) levels in hypogonadal men on anthropometric parameters. Open-label, single-center, cumulative, prospective registry study of 261 men (32-84 years, mean 59.5 ± 8.4 years, with T levels ***8804;12 nmol L-1 [mean: 7.7 ± 2.1]). Among the 261 men on T treatment, we followed up on 260 men for at least 2 years, 237 for 3 years, 195 for 4 years and 163 for at least 5 years. Subjects received parenteral T undecanoate 1000 mg every 12 weeks after an initial interval of 6 weeks. Body weight (BW), waist circumference (WC) and body mass index (BMI) were measured at baseline and yearly after treatment with T. BW decreased from 100.1 ± 14.0 kg to 92.5 ± 11.2 kg and WC was reduced from 107.7 ± 10.0 cm to 99.0 ± 9.1 cm. BMI declined from 31.7 ± 4.4 m kg-2 to 29.4 ± 3.4 m kg-2. All parameters examined were statistically significant vs. baseline and vs. the previous year over 5 years, indicating a continuous weight loss (WL) over the full observation period. The mean per cent WL was 3.2 ± 0.3% after 1 year, 5.6 ± 0.3%, after 2 years, 7.5 ± 0.3% after 3 years, 9.1 ± 0.3% after 4 years and 10.5 ± 0.4% after 5 years. The data obtained from this uncontrolled, observational, registry study suggest that raising serum T to normal physiological levels in hypogonadal men produces consistent loss in BW, WC and BMI. These marked improvements were progressive over the 5 years of the study.
     
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  3. Baylor

    Baylor Well-Known Member

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    Great topic man thanks for posting this and all the excellent information. I know for sure AAS plays a role in fat loss but I've gained fat as well as lost fat while running different compounds. The supporting cast definitely has a lot to do with that but since you mentioned only discuss the AAS portion I'll say yes they do provide support for fat loss in my opinion.
     
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  4. Vision

    Vision ★★P.S.L. Supervisor★★Vendor Rep

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    This is the type of feedback I was hoping to attack..Real first hand experience..

    I can agree how different cycles, compounds may influence body composition in either direction, and surely it's diet related with addition of wet/dry compounds.

    This is a reason why some agents are favored over the next when it concerns different goals, because it provides us with that platform assisting with less effort allowing us to focus on the target/goal..

    I can Run Nandrolone Deca during a lean or recomp, as we all know it's diet that dictates, but tren would be my go to for obvious reason. Heck I knew guys that ran dbol just weeks out, the compound doesn't make or brake, but truth of the matter is , it will assist..
     
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  5. traumajunkie

    traumajunkie Well-Known Member

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    I can't say which does what for me because diet changed with the compound. On primo I was just under maint calories and recomped amazingly. It wasn't until full prep and winny/Primo combo that holy fuck I rocked.

    NPP and I think 24-2600 calories and GH kicking in jesus I looked good at 150. And now....dieting down and just finished tbol wasn't impressed with it. May work better for a bulk for me


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  6. dsgym

    dsgym Well-Known Member

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    Everyone says "tren is great for losing fat"... while I have found that running tren did dry me out and make me lean out a bit, I've gotten to one of the highest BF %'s I have been on a tren cycle.

    That being said yes I believe strong anabolic agents will aid in fat loss. It will effect how your body used nutrients.


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  7. Vision

    Vision ★★P.S.L. Supervisor★★Vendor Rep

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    That's odd. Tren has a habit of just cobbling up nutrients at an alarming rate mostly due to the increased state of thermogensis.. Was your carb intake much higher? Could be a blood sugar related issue,maybe? By chance are you hyper or hypoglycemic? Have you noticed spikes and dips with your hunger and need for carbs?

    You can gain weight on almost anything if diet and training isn't dialed in, or if that is even the goals is to gain, not saying that in your instance that this was the case, but it's not a popular occurrence, or result!
     
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  8. dsgym

    dsgym Well-Known Member

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    Hahaha that was a 24 week tren e run. I stayed real lean then to break my plateau I ate about 450g of carbs a day. Mind you I was about 5'6" 165lbs. 450g is not low for that size.

    Nah I'm not hyper or hypoglycemic. I was just eating a LOOOOOT of carbs.




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  9. Vision

    Vision ★★P.S.L. Supervisor★★Vendor Rep

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    24 weeks of tren? Geez louise, I just wrapped up 14 weeks of Tren E, I tapped out..24 weeks "on" tren is gonzo bonzo blitz, I'd be a hot mess!

    I could definitely see where excess carbs were displaced..
     
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  10. dsgym

    dsgym Well-Known Member

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    It was a pretty low dose. I bounced back and forth between 300 and 400mg. It's doubtful I'll go that long again. I was goin a bit crazy by the end. Nearly 20 weeks of night sweats was rough.


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  11. Vision

    Vision ★★P.S.L. Supervisor★★Vendor Rep

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    That's not crazy wild for 24 weeks. in fact I fully support longer duration's at low to moderate dosages, all the while adding/subtracting orals along the way. I was running Tren E, 400mgs E4D'S, hardly any clearance time. Flatted me right out, so I dropped and switched to NPP for fullness. Next time around, cut those carbs, your night sweats will diminish, I promise. My wife tossed out enough beds and sofa's over the years because of my sweating tren ass..And, I'm not joking! :(
     
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  12. BIGVNYC

    BIGVNYC Super-ModeratorStaff Member

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    I wouldn't call steroids a fat burner with the exception to Trenbolone and the adipose fat burning properties of Anavar. When using Trenbolone on a bulk cycle with a bulk diet along with testosterone and or Npp or Eq I had always came out with atleast a 3% decrease in body fat by the end of the cycle.
     
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  13. Markg518

    Markg518 BRPHARMA RepVendor Rep

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    Good read and as I've experienced some aas can " help " in fat loss but will not alone.
    Var is the only one I know will help with actual fat loss " visceral " to a degree.

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